临床兽医学系

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  • 付本懂教授
  • 性别:男
  • 职称:教授
  • 硕导/博导:博导
  • 学科专业:临床兽医学
  • 最高学位:博士
  • 研究方向:兽医临床中药学
  • 最高学历:研究生
  • 邮箱:fubd@jlu.edu.cn

讲授课程

本科生:中兽医学、兽医针灸学

硕士生:临床兽医学进展

教育经历

2003.09-2006.07,伟德bv国际体育畜牧兽医学院,临床兽医学专业,获得博士学位

2000.09-2003.07,河北农业大学动物科技学院,临床兽医学专业,获得硕士学位

1996.09-2000.07,莱阳农学院动物科学系,兽医专业,获得学士学位

工作经历

2014.09-至今,伟德BETVlCTOR1946,教授

2012.12-2014.09,伟德BETVlCTOR1946,副教授

2009.09-2012.11,伟德bv国际体育畜牧兽医学院,副教授

2008.10-2009.10,日本北里大学兽医畜产学部,访问学者

2006.07-2009.09,伟德bv国际体育畜牧兽医学院,讲师

2003.09-2006.07,中国人民解放军军需大学,学员

科研项目

1.基于“肺与大肠相表里”研究鸡大肠杆菌病肺肠菌群的作用机制.国家自然科学基金面上项目(31972724),主持,2020.01-2023. 12

2.中兽医药现代化与绿色养殖技术研究.十三五国家重点研发计划项目课题(2017YFD0501500),主持,2017.01-2020.12

3.犬重大瘟病中兽医辨证施治关键技术研究与示范应用.公益性行业(农业)科研专项课题(201403051),主持,2014.01-2018.12.

4.香附酮抑制鸡致病性大肠杆菌侵袭肺泡Ⅱ型上皮细胞的分子机制研究.国家自然科学基金面上项目(31372470),主持,2014.01-2017.12

5. 人参皂苷Rh2衍生物促诱生IFN-γ等细胞因子作用及其靶效机制研究.国家自然科学基金青年科学基金项目(30800834),主持,2009.01-2011.12

6.中药耐药抑制剂中兽药复方的研制与开发.“十一五”国家科技支撑计划,参加,2008.01-2010.12

学术论文

代表性SCI论文如下:

1. Peng, Lu-Yuan, Shi, Hai-Tao, Tan, Yue-Rong, Shen, Si-Yang, Yi, Peng-Fei, Shen, Hai-Qing,Fu, Ben-Dong*. Baicalin inhibits APEC-induced lung injury by regulating gut microbiota and SCFA production. FOOD & FUNCTION. 2021, 12 (24): 12621-12633.

2. Lu-Yuan Peng, Hai-Tao Shi, Zi-Xuan Gong, Peng-Fei Yi *, Bo Tang, Hai-Qing Shen, Ben-Dong Fu *. Protective effects of gut microbiota and gut microbiota-derived acetate on chicken colibacillosis induced by avian pathogenic Escherichia coli. Veterinary Microbiology. 2021, 261: 109187.

3. Chen, Shuang#; Zhang, Chun-Lei#; Shen, Hai-Qing; Zhou, Xiao-Fei; Li, Jing-He; Yu, Jia-Lin; An, Qiang; Fu, Ben-Dong*; Yi, Peng-Fei*. Sesamin protects against DSS-induced colitis in mice by inhibiting NF-kappaB and MAPK signaling pathways. Food & function. 2021, 12 (4): 1688-1694 .

4. Peng LY, Shi HT, Yuan M, Li JH, Song K, Huang JN, Yi PF, Shen HQ*, Fu BD*. Madecassoside Protects Against LPS-Induced Acute Lung Injury via Inhibiting TLR4/NF-κB Activation and Blood-Air Barrier Permeability. Front Pharmacol. 2020, 11: 807.

5. Yuan M, Peng LY, Wu SC, Li JH, Song K, Chen S, Huang JN, Yu JL, An Q, Yi PF, Shen HQ*, Fu BD*. Schizandrin attenuates inflammation induced by avian pathogenic Escherichia coli in chicken type II pneumocytes. Int Immunopharmacol. 2020, 81: 106313.

6. Yuan M, Peng LY, Wei Q, Li JH, Song K, Chen S, Huang JN, Yu JL, An Q, Yi PF, Shen HQ*, Fu BD*. Schizandrin attenuates lung lesions induced by Avian pathogenic Escherichia coli in chickens. Microb Pathog. 2020 , 142: 104059.

7. Peng LY, Yuan M, Shi HT, Li JH, Song K, Huang JN, Yi PF, Fu BD*, Shen HQ*. Protective Effect of Piceatannol Against Acute Lung Injury Through Protecting the Integrity of Air-Blood Barrier and Modulating the TLR4/NF-κB Signaling Pathway Activation. Front Pharmacol. 2020, 10: 1613.

8. Peng LY#, Cui ZQ#, Wu ZM, Fu BD*, Yi PF, Shen HQ*. RNA-seq profiles of chicken type II pneumocyte in response to Escherichia coli infection. PLoS One. 2019, 14(6): e0217438.

9. Peng LY#, Yuan M#, Song K, Yu JL, Li JH, Huang JN, Yi PF, Fu BD*, Shen HQ*. Baicalin alleviated APEC-induced acute lung injury in chicken by inhibiting NF-κB pathway activation. Int Immunopharmacol. 2019, 72: 467-472.

10. Song K#, Wu ZM#, Peng LY, Yuan M, Huang JN, Zhang CL, Fu BD*, Yi PF, Shen HQ*. Canine distemper virus increased the differentiation of CD4+CD8+ T cells and mRNA expression of inflammatory cytokines in peripheral blood lymphocyte from canine. Microb Pathog. 2019, 131:254-258.

11. Peng, L.Y.#, Yuan, M., Wu, Z.M., Song, K., Zhang, Ch.L., An, Q., Xia, F., Yu, J.L., Yi, P.F., Fu, B.D.*, Shen, H.Q*. Anti-bacterial activity of baicalin against APEC through inhibition of quorum sensing and inflammatory responses. SCI REP. 2019, 9:4063.

12. Wu SC#, Yi PF#, Guo X, Zhang LY, Xu DX, Fu YX, Cui ZQ, Shen HQ, Wei XB, Fu BD*. Cinobufagin enhances the protective efficacy of formalin-inactivated Salmonella typhimurium vaccine through Th1 immune response. Microb Pathog. 2016, (99): 264-270.

13. Cui ZQ#, Wu ZM#, Fu YX, Xu DX, Guo X, Shen HQ, Wei XB, Yi PF, Fu BD*. Autoinducer-2 of quorum sensing is involved in cell damage caused by avian pathogenic Escherichia coli. Microb Pathog. 2016, (99): 247-252.

14. Zhang LY#, Yi PF#, Guo X, Wu SC, Fu YX, Zhang C, Fu BD*, Shen HQ, Wei XB. Astragaloside IV Inhibits the Inflammatory Injury of Chicken Type II Pneumocytes Induced by Avian Pathogenic Escherichia coli. Inflammation. 2016 , 39(5):1660-1669.

15. Wu SC, Fu BD, Shen HQ, Yi PF, Zhang LY, Lv S, Guo X, Xia F, Wu YL, Wei XB*. Telocinobufagin enhances the Th1 immune response and protects against Salmonella typhimurium infection. Int Immunopharmacol. 2015, 25(2):353-362.

16. Xun Guo, Li-Yan Zhang, Shuai-Cheng Wu, Fang Xia, Yun-Xing Fu, Yong-Li Wu, Chun-Qing Leng, Peng-Fei Yi, Hai-Qing Shen, Xu-Bin Wei, Ben-Dong Fu*. Andrographolide interferes quorum sensing to reduce cell damage caused by avian pathogenic Escherichia coli. Veterinary Microbiology. 2014, 174(3-4):496-503.

17. Li-Yan Zhang, Shuang Lv, Shuai-Cheng Wu, Xun Guo, Fang Xia, Xi-Rou Hu, Zhou Song, Cui Zhang, Qian-Qian Qin, Ben-Dong Fu*, Peng-Fei Yi, Hai-Qing Shen, Xu-Bin Wei. Inhibitory effects of α-cyperone on adherence and invasion of avian pathogenic Escherichia coli O78 to chicken type II pneumocytes. Veterinary Immunology and Immunopathology. 2014, 159:50-57.

18. Shuang Lv#, Peng-Fei Yi# , Hai-Qing Shen, Li-Yan Zhang, Hai-Bing Dong, Shuai-Cheng Wu, Fang Xia, Xun Guo, Xu-Bin Wei, Ben-Dong Fu*. Ginsenoside Rh2-B1 stimulates cell proliferation and IFN-γ production by activating the p38 MAPK and ERK-dependent signaling pathways in CTLL-2 cells. Immunopharmacol Immunotoxicol. 2014, 36 (1): 43-51.

19. Yi PF, Wu YC, Dong HB, Guo Y, Wei Q, Zhang C, Song Z, Qin QQ, Lv S, Wu SC, Fu BD*. Peimine impairs pro-inflammatory cytokine secretion through the inhibition of the activation of NF-κB and MAPK in LPS-induced RAW264.7 Macrophages. Immunopharmacol Immunotoxicol. 2013, 35 (5): 567-572.

20. Yi PF, Bi WY, Shen HQ, Wei Q, Zhang LY, Dong HB, Bai HL, Zhang C, Song Z, Qin QQ, Lv S, Wu SC, Fu BD*, Wei XB. Inhibitory effects of sulfated 20(S)-ginsenoside Rh2 on the release of pro-inflammatory mediators in LPS-induced RAW 264.7 cells. Eur J Pharmacol. 2013, 712: 60-66.

21. Fu BD, Bi WY, He CL, Zhu W, Shen HQ, Yi PF, Wang L, Wang DC, Wei XB*. Sulfated derivatives of 20(S)-ginsenoside Rh2 and their inhibitory effects on LPS-induced inflammatory cytokines and mediators. Fitoterapia. 2013, 84: 303-307.

22. Bi WY#, Fu BD#, Shen HQ, Wei Q, Zhang C, Song Z, Qin QQ, Li HP, Lv S, Wu SC, Yi PF, Wei XB*. Sulfated derivative of 20(S)-ginsenoside Rh2 inhibits inflammatory cytokines through MAPKs and NF-kappa B pathways in LPS-induced RAW264.7 macrophages. Inflammation. 2012, 35 (5): 1659-1668.

23. Chang-Liang He, Ben-Dong Fu*, Hai-Qing Shen, Xiao-Lin Jiang, Xu-Bin Wei*. Fumaric acid, an antibacterial component from Aloe vera L. African Journal of Biotechnology. 2011, 10 (15): 2973-2977.

24. Chang-Liang He#, Ben-Dong Fu#, Hai-Qing Shen, Xiao-Lin Jiang, Chang-Shuai Zhang, Shuai-Cheng Wu, Wei Zhu, Xu-Bin Wei*. Xiang-Qi-Tang increases APEC-induced survival rate and regulates serum levels of TNF-α, IL-1 and sEPCR in chicken. Biological & Pharmaceutical Bulletin. 2011, 34 (3): 379-382.

25. FU Ben-Dong, YAMAWAKI Hideyuki*, OKADA Muneyoshi, and HARA Yukio. Vaspin can not inhibit TNF-α-induced inflammation of human umbilical vein endothelial cells. Journal of Veterinary Medical Science. 2009, 71 (09): 1201-1207.

著作教材

1.参编,《中兽医验方与妙用精编》,北京:化学工业出版社,2019年6月

2.参编,《牛病中兽医防治》,北京:金盾出版社,2017年5月

3.参编,《中药饲料添加剂的开发与应用》(第二版),北京:化学工业出版社,2017年2月

4.参编,《中兽医学实验指导》(第三版),北京:中国农业出版社,2016年5月

5.参编,《牛常见病中西医简便疗法》,北京:金盾出版社,2015年11月

6.译者,《小动物皮肤病诊疗问与答-经典病例142》,北京:中国农业科学技术出版社,2015年8月

7.参编,《中兽医学》,北京:科学出版社,2013年7月

8.译者,《(英汉对照)元亨疗马集许序注释》,北京:中国农业出版社,2012年8月

9.副主编,《生态养鹿》,北京:中国农业出版社,2011年7月

10.副主编,《中兽医名著与方剂》,石家庄:河北科学技术出版社,2011年1月

11.副主编,《猫病学》,北京:中国农业出版社,2010年11月

12.参编,《马病妙方绝技》,北京:中国农业出版社,2010年1月

13.参编,《畜牧兽医专业英语听力教程》,上海:复旦大学出版社,2009年8月

14.参编,《新编中兽医验方与妙用》,北京:化学工业出版社,2009年3月

15.参编,《中兽医学》,北京:中国农业出版社,2006年12月

16.参编,《中药饲料添加剂的开发与应用》,北京:化学工业出版社,2005年8月

17.副主编,《野菜食疗食谱1000样》,长春:吉林科学技术出版社,2005年6月

18.参编,《鹿产品珍方与药膳》,长春:吉林科学技术出版社,2004年8月

19.参编,《英汉医学缩略语辞典》,北京:科学出版社,2004年6月

20.副主编,《中国野菜》,长春:吉林科学技术出版社,2004年6月

获奖情况

伟德bv国际体育2020-2021学年本科“课堂教学质量奖”优秀奖,202109

中国畜牧兽医学会中兽医学分会第一届“冀中杯”优秀中青年教师奖,201610

吉林省自然科学学术成果三等奖,201510

伟德bv国际体育第三届师德先进个人,201309

社会兼职

中国畜牧兽医学会中兽医学分会副理事长

亚洲中兽医学会/亚洲传统兽医学会理事

农业农村部第六、七届兽药评审专家

第五、六届中国兽药典委员会委员

吉林省动物疫病净化专家

中国兽医协会团体标准技术委员会中兽医分委会委员

中国兽医学报、中兽医学杂志编委

联系我们

公司电话:0431-87836150

动物医院电话:0431-87836297 或 87836298

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